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ndm 1 panel  (ATCC)


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  • 93

    Structured Review

    ATCC ndm 1 panel
    Ndm 1 Panel, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ndm+1+panel/NDM-1+Panel/pm40136287-120-27-35
    Average 93 stars, based on 1 article reviews
    ndm 1 panel - by Bioz Stars, 2026-09
    93/100 stars

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    Related Articles

    Expressing:

    Article Title: Discovery of Conformationally Constrained Dihydro Benzo-Indole Derivatives as Metallo-β-Lactamase Inhibitors to Tackle Multidrug-Resistant Bacterial Infections.
    Article Snippet: The discovery of metallo-β-lactamase (MBL) inhibitors is crucial in the fight against bacterial infections following the emergence and rapid spread of New Delhi metalloβ-lactamase-1 (NDM-1), as well as clinically relevant Verona integrin-encoded metallo-β-lactamase (VIM), and Imipenemase (IMP).. The situation is alarming as there are insufficient antibiotics in the pipeline to combat critical multidrug-resistant infections.. Here, we report the discovery of novel dihydrobenzoindole (dBI) derivatives as a new class of potent metallo-βlactamase inhibitors (MBLIs) by applying scaffold hopping, conformation constrained, and substituent-decorating strategies.

    Article Title: Discovery of Conformationally Constrained Dihydro Benzo-Indole Derivatives as Pan-Metallo-β-Lactamase Inhibitors to Tackle Multidrug-Resistant Bacterial Infections
    Article Snippet: Synergy studies against ATCC strains panel and clinical strains expressing NDM-1. .. To determine the potential synergistic effect of our inhibitor on various isolates, we assessed MIC of imipenem and meropenem in combination with compound 17u against NDM-1 panel of six bacterial strains obtained from ATCC and seven clinical isolates expressing NDM-1 carbapenemases. ..

    Concentration Assay:

    Article Title: Discovery of Conformationally Constrained Dihydro Benzo-Indole Derivatives as Pan-Metallo-β-Lactamase Inhibitors to Tackle Multidrug-Resistant Bacterial Infections
    Article Snippet: .. Page 22/23 Minimum inhibitory concentration of antibiotics in combination with 17u against NDM-1 panel of ATCC strains. ..

    Suspension:

    Article Title: Discovery of Conformationally Constrained Dihydro Benzo-Indole Derivatives as Pan-Metallo-β-Lactamase Inhibitors to Tackle Multidrug-Resistant Bacterial Infections
    Article Snippet: .. 95 μL of the bacterial suspension was added to each well and incubated at 37°C for 16–18 h. Synergy studies on NDM-1 panel of ATCC strains was outsourced to Foundation for Neglected Disease Research (FNDR), Bengaluru. ..

    Incubation:

    Article Title: Discovery of Conformationally Constrained Dihydro Benzo-Indole Derivatives as Pan-Metallo-β-Lactamase Inhibitors to Tackle Multidrug-Resistant Bacterial Infections
    Article Snippet: .. 95 μL of the bacterial suspension was added to each well and incubated at 37°C for 16–18 h. Synergy studies on NDM-1 panel of ATCC strains was outsourced to Foundation for Neglected Disease Research (FNDR), Bengaluru. ..



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